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Key antioxidative mechanisms include the reduction of reactive species, upregulation of endogenous antioxidants, and activation of the Nrf2-ARE pathway

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Biochem Pharmacol 119:7684 [DOI] [PMC free article] [PubMed] [Google Scholar] Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians

FEBS Lett 505(2):259263 Funai K, Parkington JD, Carambula S, Fielding RA (2006) Age-associated decrease in contraction-induced activation of downstream targets of Akt/mTor signaling in skeletal muscle

Atoms for carbon, oxygen, nitrogen, sulfur, and hydrogen are shown with double bonds at terminal carboxyl groups